About Schuyler CountySchuyler county is located in the northeastern portion of Missouri. As of the 2010 census the population was 4,431. It is located along the Missouri and Iowa border. The county seat is located in Lancaster, Missouri. Schuyler county is part of Kirksville, MO Micropolitan Statistical Area. The county was organized February 14, 1845 and was named after General Phillip Schuyler, delegate to the Continental Congress and U.S Senator from New York.
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